[1]
Le VNH, Wabnig F, Bachmann B, Cursiefen C. Epithelial downgrowth after Descemet membrane endothelial keratoplasty. European journal of ophthalmology. 2021 Mar:31(2):NP27-NP32. doi: 10.1177/1120672120912413. Epub 2020 Mar 12
[PubMed PMID: 32162534]
[2]
Vargas LG, Vroman DT, Solomon KD, Holzer MP, Escobar-Gomez M, Schmidbauer JM, Apple DJ. Epithelial downgrowth after clear cornea phacoemulsification: report of two cases and review of the literature. Ophthalmology. 2002 Dec:109(12):2331-5
[PubMed PMID: 12466179]
Level 3 (low-level) evidence
[3]
Smith RE, Parrett C. Specular microscopy of epithelial downgrowth. Archives of ophthalmology (Chicago, Ill. : 1960). 1978 Jul:96(7):1222-4
[PubMed PMID: 666630]
[4]
REGAN EF. Epithelial invasion of the anterior chamber. Transactions of the American Ophthalmological Society. 1957-1958:55():741-72
[PubMed PMID: 13556838]
[5]
Weiner MJ, Trentacoste J, Pon DM, Albert DM. Epithelial downgrowth: a 30-year clinicopathological review. The British journal of ophthalmology. 1989 Jan:73(1):6-11
[PubMed PMID: 2920156]
[6]
Wolter JR. Unusual epithelial downgrowth complicating retinal detachment surgery and ocular evisceration. American journal of ophthalmology. 1965 Oct:60(4):679-84
[PubMed PMID: 5841576]
[7]
Itty S, Proia AD, DelMonte DW, Santaella RM, Carlson A, Allingham RR. Clinical course and origin of epithelium in cases of epithelial downgrowth after Descemet stripping automated endothelial keratoplasty. Cornea. 2014 Nov:33(11):1140-4. doi: 10.1097/ICO.0000000000000234. Epub
[PubMed PMID: 25188788]
Level 3 (low-level) evidence
[8]
Hu J, Goldstein DA, Leiderman YI, Malhotra V, Chau FY, Lin AY, Vajaranant TS. Epithelial downgrowth after Ahmed implantation presenting as a peritubular fibrovascular membrane. Journal of glaucoma. 2013 Aug:22(6):e11-3. doi: 10.1097/IJG.0b013e318255d9ee. Epub
[PubMed PMID: 23899696]
[9]
Bielory BP, Jacobs D, Alfonso E, Perez VL, Dubovy SR, Berrocal A. Epithelial downgrowth after type 1 Boston keratoprosthesis manifesting as tractional retinal detachment and epiretinal membrane. Archives of ophthalmology (Chicago, Ill. : 1960). 2012 Jan:130(1):118-20. doi: 10.1001/archopthalmol.2011.1238. Epub
[PubMed PMID: 22232484]
[10]
CHRISTENSEN L. Epithelization of the anterior chamber. Transactions of the American Ophthalmological Society. 1960:58():284-300
[PubMed PMID: 13693361]
[11]
Sugar A, Meyer RF, Hood CI. Epithelial downgrowth following penetrating keratoplasty in the aphake. Archives of ophthalmology (Chicago, Ill. : 1960). 1977 Mar:95(3):464-7
[PubMed PMID: 320971]
[12]
Kim SK, Ibarra MS, Syed NA, Sulewski ME, Orlin SE. Development of epithelial downgrowth several decades after intraocular surgery. Cornea. 2005 Jan:24(1):108-9
[PubMed PMID: 15604876]
[13]
Rosentreter A, Schild AM, Wedemeyer I, Dietlein TS. [Epithelial downgrowth 48 years after penetrating eye trauma]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 2010 Aug:107(8):753-6. doi: 10.1007/s00347-009-2121-z. Epub
[PubMed PMID: 20376459]
[14]
Mansour AM. Combined intracorneal and subconjunctival bevacizumab injections for recurrent visual loss and intraocular hemorrhage from vascularized fibrous downgrowth. Case reports in ophthalmology. 2014 Jan:5(1):28-33. doi: 10.1159/000358167. Epub 2014 Jan 15
[PubMed PMID: 24575035]
Level 3 (low-level) evidence
[15]
Walker BM, Hindman HB, Ebrahimi KB, Green WR, Eberhart CG, Garcia I, Jun AS. Epithelial downgrowth following Descemet's-stripping automated endothelial keratoplasty. Archives of ophthalmology (Chicago, Ill. : 1960). 2008 Feb:126(2):278-80. doi: 10.1001/archophthalmol.2007.58. Epub
[PubMed PMID: 18268229]
[16]
Patel HR, Margo CE. Epithelial downgrowth. Report of 2 cases diagnosed by ocular biopsy. Annals of diagnostic pathology. 2017 Feb:26():60-63. doi: 10.1016/j.anndiagpath.2016.10.004. Epub 2016 Oct 14
[PubMed PMID: 28209236]
Level 3 (low-level) evidence
[17]
Ganesh A, Al-Fadhil N, Wali U, Bialasiewicz AA. En bloc excision of intraocular epithelial cystic downgrowth using syngeneic auricular cartilage. Eye (London, England). 2005 Jan:19(1):97-100
[PubMed PMID: 15286674]
[18]
Chee PH. Epithelial downgrowth. Archives of ophthalmology (Chicago, Ill. : 1960). 1967 Oct:78(4):492-5
[PubMed PMID: 6046845]
[19]
Mihail Z, Alina-Cristina S, Speranta S. Retrocorneal membranes after penetrating keratoplasty. Romanian journal of ophthalmology. 2015 Oct-Dec:59(4):230-234
[PubMed PMID: 29450312]
[20]
Majmudar PA, Epstein RJ, Parent A, Raphtis EM, Grostern R, Torczynski E. Noninvasive diagnosis of epithelial downgrowth after penetrating keratoplasty using immunohistochemical analysis of resected corneal buttons. Cornea. 2006 Jul:25(6):727-33
[PubMed PMID: 17077669]
[21]
Lenhart PD, Randleman JB, Grossniklaus HE, Stulting RD. Confocal microscopic diagnosis of epithelial downgrowth. Cornea. 2008 Dec:27(10):1138-41. doi: 10.1097/ICO.0b013e3181815959. Epub
[PubMed PMID: 19034128]
[22]
Chen MC, Cortés DE, Harocopos G, Mannis MJ. Epithelial downgrowth after penetrating keratoplasty: imaging by high-resolution optical coherence tomography and in vivo confocal microscopy. Cornea. 2013 Nov:32(11):1505-8. doi: 10.1097/ICO.0b013e31829c6d13. Epub
[PubMed PMID: 23928949]
[23]
Suh LH, Shousha MA, Ventura RU, Kieval JZ, Perez VL, Wang J, Dubovy SR, Rosenfeld SI, Culbertson WW, Alfonso EC, Forster RK. Epithelial ingrowth after Descemet stripping automated endothelial keratoplasty: description of cases and assessment with anterior segment optical coherence tomography. Cornea. 2011 May:30(5):528-34. doi: 10.1097/ICO.0b013e3181fb8149. Epub
[PubMed PMID: 21107249]
Level 3 (low-level) evidence
[24]
Diel RJ,Morrow NC,Jiang L,Huffman JM,Greiner MA, Transcorneal Cryotherapy and Descemet Membrane Endothelial Keratoplasty to Treat Epithelial Downgrowth and Corneal Decompensation After Cataract Surgery. Cornea. 2020 Mar 24;
[PubMed PMID: 32243422]
[25]
Han KE, Kim CY, Chung JL, Hong JP, Sgrignoli B, Kim EK. Successful argon laser photocoagulation of diffuse epithelial ingrowth following concomitant persistent pupillary membrane removal and phacoemulsification. Journal of cataract and refractive surgery. 2012 May:38(5):906-11. doi: 10.1016/j.jcrs.2012.02.005. Epub 2012 Mar 2
[PubMed PMID: 22386278]
[26]
Yu CS, Chiu SI, Tse RK. Treatment of cystic epithelial downgrowth with intralesional administration of mitomycin C. Cornea. 2005 Oct:24(7):884-6
[PubMed PMID: 16160512]
[27]
Jadav DS, Rylander NR, Vold SD, Fulcher SF, Rosa RH Jr. Endoscopic photocoagulation in the management of epithelial downgrowth. Cornea. 2008 Jun:27(5):601-4. doi: 10.1097/ICO.0b013e318165b1e0. Epub
[PubMed PMID: 18520512]
[28]
Abdollah Z,Mohd Zahidin AZ,Ahem A,Abdul Rahman R,Md Din N, Successful treatment of epithelial downgrowth with endoscopic photocoagulation and intracameral 5-fluorouracil after prolonged limbal wound leak. International journal of ophthalmology. 2018;
[PubMed PMID: 29675395]
[29]
Wong RK, Greene DP, Shield DR, Eberhart CG, Huang JJ, Shayegani A. 5-Fluorouracil for epithelial downgrowth after Descemet stripping automated endothelial keratoplasty. Cornea. 2013 Dec:32(12):1610-2. doi: 10.1097/ICO.0b013e3182a9fc85. Epub
[PubMed PMID: 24113368]
[30]
Ni N, Goldberg MA, Eagle RC Jr, Rapuano CJ, Haller JA. Epithelial Downgrowth after Intraocular Surgery Treated with Intracameral 5-Fluorouracil. Case reports in ophthalmological medicine. 2015:2015():325485. doi: 10.1155/2015/325485. Epub 2015 May 28
[PubMed PMID: 26106497]
Level 3 (low-level) evidence
[31]
Lai MM, Haller JA. Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil. American journal of ophthalmology. 2002 Apr:133(4):562-4
[PubMed PMID: 11931795]
[32]
Shaikh AA, Damji KF, Mintsioulis G, Gupta SK, Kertes PJ. Bilateral epithelial downgrowth managed in one eye with intraocular 5-fluorouracil. Archives of ophthalmology (Chicago, Ill. : 1960). 2002 Oct:120(10):1396-8
[PubMed PMID: 12365927]
[33]
Lambert NG, Wilson DJ, Albert DM, Chamberlain WD. Intravitreal Methotrexate for Recurrent Epithelial Downgrowth. JAMA ophthalmology. 2019 Sep 1:137(9):1082-1083. doi: 10.1001/jamaophthalmol.2019.2151. Epub
[PubMed PMID: 31246261]
[34]
Haller JA, Stark WJ, Azab A, Thomsen RW, Gottsch JD. Surgical management of anterior chamber epithelial cysts. American journal of ophthalmology. 2003 Mar:135(3):309-13
[PubMed PMID: 12614747]
[35]
Naumann GO,Rummelt V, Block excision of cystic and diffuse epithelial ingrowth of the anterior chamber. Report on 32 consecutive patients. Archives of ophthalmology (Chicago, Ill. : 1960). 1992 Feb;
[PubMed PMID: 1736872]
[36]
Forster RK. Corneoscleral block excision of postoperative anterior chamber cysts. Transactions of the American Ophthalmological Society. 1995:93():83-97; discussion 97-104
[PubMed PMID: 8719672]
[37]
Scarpa G, La Gloria Valerio A, Urban F, Laurino L. Epithelial downgrowth after cataract surgery: an atypical presentation with scleral thinning and massive seeding in anterior chamber. European journal of ophthalmology. 2016 Feb 15:26(2):e27-9. doi: 10.5301/ejo.5000705. Epub 2016 Feb 15
[PubMed PMID: 26559933]
[38]
Hwang DG, Smith RE. Corneal complications of cataract surgery. Refractive & corneal surgery. 1991 Jan-Feb:7(1):77-80
[PubMed PMID: 2043552]
[39]
Rummelt V, Lang GK, Yanoff M, Naumann GO. A 32-year follow-up of the rigid Schreck anterior chamber lens. A clinicopathological correlation. Archives of ophthalmology (Chicago, Ill. : 1960). 1990 Mar:108(3):401-4
[PubMed PMID: 2310344]
[40]
Levy MH, Margo CE. Fibrous Downgrowth Complicating Implantation of Intraocular Telescope. Ophthalmology. 2017 Jun:124(6):895. doi: 10.1016/j.ophtha.2016.12.019. Epub
[PubMed PMID: 28528832]
[41]
Kremer I, Zandbank J, Barash D, Ben-David E, Yassur Y. Extensive fibrous downgrowth after traumatic corneoscleral wound dehiscence. Annals of ophthalmology. 1991 Dec:23(12):465-8
[PubMed PMID: 1785905]
[42]
Smith MF, Doyle JW. Glaucoma secondary to epithelial and fibrous downgrowth. Seminars in ophthalmology. 1994 Dec:9(4):248-53
[PubMed PMID: 10155645]
[43]
Ng Jy, Srinivasan S, Roberts F. Fibrous proliferation into anterior segment after acute angle-closure glaucoma. Cornea. 2015 Jan:34(1):103-6. doi: 10.1097/ICO.0000000000000313. Epub
[PubMed PMID: 25411932]
[44]
Rummelt V, Naumann GO. [Block excision with tectonic corneoscleroplasty for cystic and/or diffuse epithelial invasion of the anterior eye segment. Report of 51 consecutive patients (1980-1996)]. Klinische Monatsblatter fur Augenheilkunde. 1997 Nov:211(5):312-23
[PubMed PMID: 9527589]
[45]
Jaber RM, Harrod M, Goshe JM. Spontaneous regression of epithelial downgrowth from clear corneal phacoemulsification wound. American journal of ophthalmology case reports. 2018 Jun:10():159-162. doi: 10.1016/j.ajoc.2018.02.020. Epub 2018 Feb 27
[PubMed PMID: 29780928]
Level 3 (low-level) evidence
[46]
Rachitskaya AV, Dubovy SR, Hussain RM, Perez VL, Alfonso EC, Berrocal AM. EPITHELIAL DOWNGROWTH IN THE VITREOUS CAVITY AND ON THE RETINA IN ENUCLEATED SPECIMENS AND IN EYES WITH VISUAL POTENTIAL. Retina (Philadelphia, Pa.). 2015 Aug:35(8):1688-95. doi: 10.1097/IAE.0000000000000495. Epub
[PubMed PMID: 25768250]