[1]
Mandell E, Kinsella JP, Abman SH. Persistent pulmonary hypertension of the newborn. Pediatric pulmonology. 2021 Mar:56(3):661-669. doi: 10.1002/ppul.25073. Epub
[PubMed PMID: 32930508]
[2]
Hernández-Díaz S, Van Marter LJ, Werler MM, Louik C, Mitchell AA. Risk factors for persistent pulmonary hypertension of the newborn. Pediatrics. 2007 Aug:120(2):e272-82
[PubMed PMID: 17671038]
[3]
Kumar VH, Hutchison AA, Lakshminrusimha S, Morin FC 3rd, Wynn RJ, Ryan RM. Characteristics of pulmonary hypertension in preterm neonates. Journal of perinatology : official journal of the California Perinatal Association. 2007 Apr:27(4):214-9
[PubMed PMID: 17330053]
[4]
Huybrechts KF, Bateman BT, Palmsten K, Desai RJ, Patorno E, Gopalakrishnan C, Levin R, Mogun H, Hernandez-Diaz S. Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn. JAMA. 2015 Jun 2:313(21):2142-51. doi: 10.1001/jama.2015.5605. Epub
[PubMed PMID: 26034955]
[5]
Alano MA, Ngougmna E, Ostrea EM Jr, Konduri GG. Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn. Pediatrics. 2001 Mar:107(3):519-23
[PubMed PMID: 11230592]
[6]
Walsh-Sukys MC, Tyson JE, Wright LL, Bauer CR, Korones SB, Stevenson DK, Verter J, Stoll BJ, Lemons JA, Papile LA, Shankaran S, Donovan EF, Oh W, Ehrenkranz RA, Fanaroff AA. Persistent pulmonary hypertension of the newborn in the era before nitric oxide: practice variation and outcomes. Pediatrics. 2000 Jan:105(1 Pt 1):14-20
[PubMed PMID: 10617698]
[7]
Steurer MA, Jelliffe-Pawlowski LL, Baer RJ, Partridge JC, Rogers EE, Keller RL. Persistent Pulmonary Hypertension of the Newborn in Late Preterm and Term Infants in California. Pediatrics. 2017 Jan:139(1):. pii: e20161165. doi: 10.1542/peds.2016-1165. Epub 2016 Dec 1
[PubMed PMID: 27940508]
[8]
Steurer MA, Baer RJ, Oltman S, Ryckman KK, Feuer SK, Rogers E, Keller RL, Jelliffe-Pawlowski LL. Morbidity of Persistent Pulmonary Hypertension of the Newborn in the First Year of Life. The Journal of pediatrics. 2019 Oct:213():58-65.e4. doi: 10.1016/j.jpeds.2019.06.053. Epub 2019 Aug 6
[PubMed PMID: 31399244]
[9]
Lakshminrusimha S, Steinhorn RH. Pulmonary vascular biology during neonatal transition. Clinics in perinatology. 1999 Sep:26(3):601-19
[PubMed PMID: 10494467]
[10]
Farrow KN, Lee KJ, Perez M, Schriewer JM, Wedgwood S, Lakshminrusimha S, Smith CL, Steinhorn RH, Schumacker PT. Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxidants & redox signaling. 2012 Aug 1:17(3):460-70. doi: 10.1089/ars.2011.4184. Epub 2012 Mar 8
[PubMed PMID: 22229392]
[11]
Gaston BM, Carver J, Doctor A, Palmer LA. S-nitrosylation signaling in cell biology. Molecular interventions. 2003 Aug:3(5):253-63
[PubMed PMID: 14993439]
[12]
Mata-Greenwood E, Jenkins C, Farrow KN, Konduri GG, Russell JA, Lakshminrusimha S, Black SM, Steinhorn RH. eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally. American journal of physiology. Lung cellular and molecular physiology. 2006 Feb:290(2):L232-41
[PubMed PMID: 16143585]
[13]
Singh Y, Lakshminrusimha S. Pathophysiology and Management of Persistent Pulmonary Hypertension of the Newborn. Clinics in perinatology. 2021 Aug:48(3):595-618. doi: 10.1016/j.clp.2021.05.009. Epub
[PubMed PMID: 34353582]
[14]
Jain A, McNamara PJ. Persistent pulmonary hypertension of the newborn: Advances in diagnosis and treatment. Seminars in fetal & neonatal medicine. 2015 Aug:20(4):262-71. doi: 10.1016/j.siny.2015.03.001. Epub 2015 Apr 2
[PubMed PMID: 25843770]
Level 3 (low-level) evidence
[15]
Bendapudi P, Rao GG, Greenough A. Diagnosis and management of persistent pulmonary hypertension of the newborn. Paediatric respiratory reviews. 2015 Jun:16(3):157-61. doi: 10.1016/j.prrv.2015.02.001. Epub 2015 Feb 10
[PubMed PMID: 25765845]
[16]
Lakshminrusimha S, Keszler M. Persistent Pulmonary Hypertension of the Newborn. NeoReviews. 2015 Dec:16(12):e680-e692
[PubMed PMID: 26783388]
[17]
Peterson AL, Deatsman S, Frommelt MA, Mussatto K, Frommelt PC. Correlation of echocardiographic markers and therapy in persistent pulmonary hypertension of the newborn. Pediatric cardiology. 2009 Feb:30(2):160-5. doi: 10.1007/s00246-008-9303-3. Epub 2008 Sep 9
[PubMed PMID: 18779989]
[18]
Reynolds EW, Ellington JG, Vranicar M, Bada HS. Brain-type natriuretic peptide in the diagnosis and management of persistent pulmonary hypertension of the newborn. Pediatrics. 2004 Nov:114(5):1297-304
[PubMed PMID: 15520111]
[19]
Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR. Inhaled nitric oxide inhibits NOS activity in lambs: potential mechanism for rebound pulmonary hypertension. The American journal of physiology. 1999 Nov:277(5):H1849-56. doi: 10.1152/ajpheart.1999.277.5.H1849. Epub
[PubMed PMID: 10564139]
[20]
Lakshminrusimha S, Steinhorn RH. Inodilators in nitric oxide resistant persistent pulmonary hypertension of the newborn. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2013 Jan:14(1):107-9. doi: 10.1097/PCC.0b013e318250af44. Epub
[PubMed PMID: 23295841]
[21]
Lakshminrusimha S, Russell JA, Steinhorn RH, Swartz DD, Ryan RM, Gugino SF, Wynn KA, Kumar VH, Mathew B, Kirmani K, Morin FC 3rd. Pulmonary hemodynamics in neonatal lambs resuscitated with 21%, 50%, and 100% oxygen. Pediatric research. 2007 Sep:62(3):313-8
[PubMed PMID: 17622960]
[22]
Clark RH, Yoder BA, Sell MS. Prospective, randomized comparison of high-frequency oscillation and conventional ventilation in candidates for extracorporeal membrane oxygenation. The Journal of pediatrics. 1994 Mar:124(3):447-54
[PubMed PMID: 8120720]
Level 1 (high-level) evidence
[23]
Lotze A, Mitchell BR, Bulas DI, Zola EM, Shalwitz RA, Gunkel JH. Multicenter study of surfactant (beractant) use in the treatment of term infants with severe respiratory failure. Survanta in Term Infants Study Group. The Journal of pediatrics. 1998 Jan:132(1):40-7
[PubMed PMID: 9469998]
Level 2 (mid-level) evidence
[24]
. UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK Collaborative ECMO Trail Group. Lancet (London, England). 1996 Jul 13:348(9020):75-82
[PubMed PMID: 8676720]
Level 1 (high-level) evidence
[25]
Roberts JD Jr, Fineman JR, Morin FC 3rd, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM. Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. The New England journal of medicine. 1997 Feb 27:336(9):605-10
[PubMed PMID: 9032045]
[26]
Clark RH, Kueser TJ, Walker MW, Southgate WM, Huckaby JL, Perez JA, Roy BJ, Keszler M, Kinsella JP. Low-dose nitric oxide therapy for persistent pulmonary hypertension of the newborn. Clinical Inhaled Nitric Oxide Research Group. The New England journal of medicine. 2000 Feb 17:342(7):469-74
[PubMed PMID: 10675427]
[27]
Konduri GG, Solimano A, Sokol GM, Singer J, Ehrenkranz RA, Singhal N, Wright LL, Van Meurs K, Stork E, Kirpalani H, Peliowski A, Neonatal Inhaled Nitric Oxide Study Group. A randomized trial of early versus standard inhaled nitric oxide therapy in term and near-term newborn infants with hypoxic respiratory failure. Pediatrics. 2004 Mar:113(3 Pt 1):559-64
[PubMed PMID: 14993550]
Level 1 (high-level) evidence
[28]
McNamara PJ, Shivananda SP, Sahni M, Freeman D, Taddio A. Pharmacology of milrinone in neonates with persistent pulmonary hypertension of the newborn and suboptimal response to inhaled nitric oxide. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2013 Jan:14(1):74-84. doi: 10.1097/PCC.0b013e31824ea2cd. Epub
[PubMed PMID: 23132395]
[29]
James AT, Corcoran JD, McNamara PJ, Franklin O, El-Khuffash AF. The effect of milrinone on right and left ventricular function when used as a rescue therapy for term infants with pulmonary hypertension. Cardiology in the young. 2016 Jan:26(1):90-9. doi: 10.1017/S1047951114002698. Epub 2015 Jan 20
[PubMed PMID: 25599873]
[30]
Baquero H, Soliz A, Neira F, Venegas ME, Sola A. Oral sildenafil in infants with persistent pulmonary hypertension of the newborn: a pilot randomized blinded study. Pediatrics. 2006 Apr:117(4):1077-83
[PubMed PMID: 16585301]
Level 3 (low-level) evidence
[31]
Steinhorn RH, Kinsella JP, Pierce C, Butrous G, Dilleen M, Oakes M, Wessel DL. Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension. The Journal of pediatrics. 2009 Dec:155(6):841-847.e1. doi: 10.1016/j.jpeds.2009.06.012. Epub
[PubMed PMID: 19836028]
[32]
Lai MY, Chu SM, Lakshminrusimha S, Lin HC. Beyond the inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Pediatrics and neonatology. 2018 Feb:59(1):15-23. doi: 10.1016/j.pedneo.2016.09.011. Epub 2017 Aug 10
[PubMed PMID: 28923474]
[33]
Mugford M, Elbourne D, Field D. Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants. The Cochrane database of systematic reviews. 2008 Jul 16:(3):CD001340. doi: 10.1002/14651858.CD001340.pub2. Epub 2008 Jul 16
[PubMed PMID: 18646070]
Level 1 (high-level) evidence
[34]
Davis PJ, Firmin RK, Manktelow B, Goldman AP, Davis CF, Smith JH, Cassidy JV, Shekerdemian LS. Long-term outcome following extracorporeal membrane oxygenation for congenital diaphragmatic hernia: the UK experience. The Journal of pediatrics. 2004 Mar:144(3):309-15
[PubMed PMID: 15001933]
[35]
Konduri GG, Vohr B, Robertson C, Sokol GM, Solimano A, Singer J, Ehrenkranz RA, Singhal N, Wright LL, Van Meurs K, Stork E, Kirpalani H, Peliowski A, Johnson Y, Neonatal Inhaled Nitric Oxide Study Group. Early inhaled nitric oxide therapy for term and near-term newborn infants with hypoxic respiratory failure: neurodevelopmental follow-up. The Journal of pediatrics. 2007 Mar:150(3):235-40, 240.e1
[PubMed PMID: 17307536]
[36]
Robertson CM, Tyebkhan JM, Hagler ME, Cheung PY, Peliowski A, Etches PC. Late-onset, progressive sensorineural hearing loss after severe neonatal respiratory failure. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2002 May:23(3):353-6
[PubMed PMID: 11981395]
[37]
Lipkin PH, Davidson D, Spivak L, Straube R, Rhines J, Chang CT. Neurodevelopmental and medical outcomes of persistent pulmonary hypertension in term newborns treated with nitric oxide. The Journal of pediatrics. 2002 Mar:140(3):306-10
[PubMed PMID: 11953727]
[38]
Reuter S, Moser C, Baack M. Respiratory distress in the newborn. Pediatrics in review. 2014 Oct:35(10):417-28; quiz 429. doi: 10.1542/pir.35-10-417. Epub
[PubMed PMID: 25274969]
[39]
Malowitz JR, Forsha DE, Smith PB, Cotten CM, Barker PC, Tatum GH. Right ventricular echocardiographic indices predict poor outcomes in infants with persistent pulmonary hypertension of the newborn. European heart journal. Cardiovascular Imaging. 2015 Nov:16(11):1224-31. doi: 10.1093/ehjci/jev071. Epub 2015 Apr 6
[PubMed PMID: 25851325]