[1]
BLACK GW, McARDLE L. The effects of halothane on the peripheral circulation in man. British journal of anaesthesia. 1962 Jan:34():2-10
[PubMed PMID: 13869652]
[2]
Black GW. A review of the pharmacology of halothane. British journal of anaesthesia. 1965 Sep:37(9):688-705
[PubMed PMID: 5320091]
[3]
Stachnik J. Inhaled anesthetic agents. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2006 Apr 1:63(7):623-34
[PubMed PMID: 16554286]
[5]
Eger EI 2nd, Saidman LJ, Brandstater B. Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology. 1965 Nov-Dec:26(6):756-63
[PubMed PMID: 5844267]
[6]
Brown BR Jr. Halothane hepatitis revisited. The New England journal of medicine. 1985 Nov 21:313(21):1347-8
[PubMed PMID: 4058525]
[7]
Carney FM, Van Dyke RA. Halothane hepatitis: a critical review. Anesthesia and analgesia. 1972 Jan-Feb:51(1):135-60
[PubMed PMID: 4399967]
[8]
Massart J, Begriche K, Moreau C, Fromenty B. Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity. Journal of clinical and translational research. 2017 Feb:3(Suppl 1):212-232. doi: 10.18053/jctres.03.2017S1.006. Epub 2017 Feb 12
[PubMed PMID: 28691103]
[9]
Peters RL, Edmondson HA, Reynolds TB, Meister JC, Curpey TJ. Hepatic necrosis associated with halothane anesthesia. The American journal of medicine. 1969 Nov:47(5):748-64
[PubMed PMID: 5352203]
[10]
Shingu K, Eger EI 2nd, Johnson BH, Van Dyke RA, Lurz FW, Cheng A. Effect of oxygen concentration, hyperthermia, and choice of vendor on anesthetic-induced hepatic injury in rats. Anesthesia and analgesia. 1983 Feb:62(2):146-50
[PubMed PMID: 6829915]
[11]
Shingu K, Eger EI 2nd, Johnson BH. Hypoxia per se can produce hepatic damage without death in rats. Anesthesia and analgesia. 1982 Oct:61(10):820-3
[PubMed PMID: 6812462]
[12]
Njoku DB. Drug-induced hepatotoxicity: metabolic, genetic and immunological basis. International journal of molecular sciences. 2014 Apr 22:15(4):6990-7003. doi: 10.3390/ijms15046990. Epub 2014 Apr 22
[PubMed PMID: 24758937]
[13]
Hoft RH, Bunker JP, Goodman HI, Gregory PB. Halothane hepatitis in three pairs of closely related women. The New England journal of medicine. 1981 Apr 23:304(17):1023-4
[PubMed PMID: 7207555]
[14]
Böttiger LE, Dalén E, Hallén B. Halothane-induced liver damage: an analysis of the material reported to the Swedish Adverse Drug Reaction Committee, 1966-1973. Acta anaesthesiologica Scandinavica. 1976:20(1):40-6
[PubMed PMID: 1266555]
[15]
Inman WH, Mushin WW. Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines. British medical journal. 1974 Jan 5:1(5896):5-10
[PubMed PMID: 4808831]
[16]
. Summary of the national Halothane Study. Possible association between halothane anesthesia and postoperative hepatic necrosis. JAMA. 1966 Sep 5:197(10):775-88
[PubMed PMID: 5953371]
[17]
Gut J, Christen U, Huwyler J. Mechanisms of halothane toxicity: novel insights. Pharmacology & therapeutics. 1993:58(2):133-55
[PubMed PMID: 8415876]
[18]
Huang L, Sang CN, Desai MS. Beyond Ether and Chloroform-A Major Breakthrough With Halothane. Journal of anesthesia history. 2017 Jul:3(3):87-102. doi: 10.1016/j.janh.2017.05.003. Epub 2017 Jun 3
[PubMed PMID: 28842156]
[19]
Walton B, Simpson BR, Strunin L, Doniach D, Perrin J, Appleyard AJ. Unexplained hepatitis following halothane. British medical journal. 1976 May 15:1(6019):1171-6
[PubMed PMID: 1268612]
[20]
Black GW, Clarke RS. Recently introduced anesthetic drugs. International anesthesiology clinics. 1971 Fall:9(3):171-96
[PubMed PMID: 4951005]
[21]
Stevens WC. New halogenated anesthetics: enflurane and isoflurane. California medicine. 1972 Oct:117(4):47
[PubMed PMID: 18730834]
[22]
Cousins MJ, Plummer JL, Hall PD. Risk factors for halothane hepatitis. The Australian and New Zealand journal of surgery. 1989 Jan:59(1):5-14
[PubMed PMID: 2643940]
[23]
Safari S, Motavaf M, Seyed Siamdoust SA, Alavian SM. Hepatotoxicity of halogenated inhalational anesthetics. Iranian Red Crescent medical journal. 2014 Sep:16(9):e20153. doi: 10.5812/ircmj.20153. Epub 2014 Sep 5
[PubMed PMID: 25593732]
[24]
BUNKER JP, BLUMENFELD CM. Liver necrosis after halothane anesthesia. Cause or coincidence? The New England journal of medicine. 1963 Mar 7:268():531-4
[PubMed PMID: 14016845]
[25]
Neuberger JM. Halothane and hepatitis. Incidence, predisposing factors and exposure guidelines. Drug safety. 1990 Jan-Feb:5(1):28-38
[PubMed PMID: 2178633]
[26]
Sigurdsson GH, Lindahl S. Cardiac arrhythmias in intubated children during adenoidectomy. A comparison between enflurane and halothane anaesthesia. Acta anaesthesiologica Scandinavica. 1983 Dec:27(6):484-9
[PubMed PMID: 6666527]
[28]
Chang CY, Schiano TD. Review article: drug hepatotoxicity. Alimentary pharmacology & therapeutics. 2007 May 15:25(10):1135-51
[PubMed PMID: 17451560]
[29]
Yuan L, Kaplowitz N. Mechanisms of drug-induced liver injury. Clinics in liver disease. 2013 Nov:17(4):507-18, vii. doi: 10.1016/j.cld.2013.07.002. Epub 2013 Aug 1
[PubMed PMID: 24099014]
[30]
Kharasch ED. Adverse drug reactions with halogenated anesthetics. Clinical pharmacology and therapeutics. 2008 Jul:84(1):158-62. doi: 10.1038/clpt.2008.97. Epub 2008 May 28
[PubMed PMID: 18509326]
[31]
Spracklin DK, Thummel KE, Kharasch ED. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4. Drug metabolism and disposition: the biological fate of chemicals. 1996 Sep:24(9):976-83
[PubMed PMID: 8886607]
[32]
Sipes IG, Gandolfi AJ, Pohl LR, Krishna G, Brown BR Jr. Comparison of the biotransformation and hepatotoxicity of halothane and deuterated halothane. The Journal of pharmacology and experimental therapeutics. 1980 Sep:214(3):716-20
[PubMed PMID: 7400974]
[33]
Spracklin DK, Hankins DC, Fisher JM, Thummel KE, Kharasch ED. Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro. The Journal of pharmacology and experimental therapeutics. 1997 Apr:281(1):400-11
[PubMed PMID: 9103523]
[34]
de Groot H, Noll T. Halothane hepatotoxicity: relation between metabolic activation, hypoxia, covalent binding, lipid peroxidation and liver cell damage. Hepatology (Baltimore, Md.). 1983 Jul-Aug:3(4):601-6
[PubMed PMID: 6345332]
[36]
Kharasch ED, Hankins DC, Fenstamaker K, Cox K. Human halothane metabolism, lipid peroxidation, and cytochromes P(450)2A6 and P(450)3A4. European journal of clinical pharmacology. 2000 Feb-Mar:55(11-12):853-9
[PubMed PMID: 10805064]
[37]
Gut J. Molecular basis of halothane hepatitis. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. 1998:20():3-17
[PubMed PMID: 9442277]
[38]
Kenna JG, Neuberger J, Williams R. Evidence for expression in human liver of halothane-induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis. Hepatology (Baltimore, Md.). 1988 Nov-Dec:8(6):1635-41
[PubMed PMID: 3192177]
[39]
Morio M, Fujii K, Yuge O. Current concept of halothane hepatitis (review). In vivo (Athens, Greece). 1987 May-Jun:1(3):163-6
[PubMed PMID: 2979781]
[40]
Nimmo WS, Thompson PG, Prescott LF. Microsomal enzyme induction after halothane anaesthesia. British journal of clinical pharmacology. 1981 Sep:12(3):433-4
[PubMed PMID: 7295475]
[41]
Brown BR Jr, Gandolfi AJ. Adverse effects of volatile anaesthetics. British journal of anaesthesia. 1987 Jan:59(1):14-23
[PubMed PMID: 3548786]
[42]
Lo SK, Wendon J, Mieli-Vergani G, Williams R. Halothane-induced acute liver failure: continuing occurrence and use of liver transplantation. European journal of gastroenterology & hepatology. 1998 Aug:10(8):635-9
[PubMed PMID: 9744690]
[43]
Wright R, Eade OE, Chisholm M, Hawksley M, Lloyd B, Moles TM, Edwards JC, GArdner MJ. Controlled prospective study of the effect on liver function of multiple exposures to halothane. Lancet (London, England). 1975 Apr 12:1(7911):817-20
[PubMed PMID: 48053]
[44]
Mushin WW, Rosen M, Jones EV. Post-halothane jaundice in relation to previous administration of halothane. British medical journal. 1971 Jul 3:3(5765):18-22
[PubMed PMID: 5091889]
[45]
Kenna JG, Neuberger J, Mieli-Vergani G, Mowat AP, Williams R. Halothane hepatitis in children. British medical journal (Clinical research ed.). 1987 May 9:294(6581):1209-11
[PubMed PMID: 3109584]
[47]
Moore DH, Benson GD. Prolonged halothane hepatitis. Prompt resolution of severe lesion with corticosteroid therapy. Digestive diseases and sciences. 1986 Nov:31(11):1269-72
[PubMed PMID: 3769709]
[48]
Sigston PE, Jenkins AM, Jackson EA, Sury MR, Mackersie AM, Hatch DJ. Rapid inhalation induction in children: 8% sevoflurane compared with 5% halothane. British journal of anaesthesia. 1997 Apr:78(4):362-5
[PubMed PMID: 9135351]