Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 6,204 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 6,204 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 3,481 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to system and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 2,859 authors and 46 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

  • How many questions is the SPEX Exam?

  • What topics are covered on the SPEX Exam?

SPEX Exam MCQs (6,204)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

31 Questions

Level 2

601 Questions

Level 3

4,455 Questions

Level 4

1,117 Questions

  • Allergy and Immunology - 320 questions
  • Cardiovascular - 1540 questions
  • Musculoskeletal - 1079 questions
  • Ears Nose and Throat - 320 questions
  • Endocrine and Metabolism - 771 questions
  • Ophthalmology - 258 questions
  • Gastrointestinal and Nutrition - 1342 questions
  • Renal, Urinary and Electrolytes - 702 questions
  • Human Growth and Development - 249 questions
  • Gynecologic - 246 questions
  • Hematology and Oncology - 1034 questions
  • Infectious Diseases - 1611 questions
  • Dermatology - 600 questions
  • Nervous - 1386 questions
  • Pregnancy, Childbirth & Puerperium - 245 questions
  • Psychiatric/Behavioral & Substance Use Disorder - 517 questions
  • Pulmonary & Critical Care - 920 questions
  • Poisoning & Environmental Exposure - 1120 questions
  • Biostatistics and Epidemiology - 208 questions
  • Dental - 34 questions
  • Reproductive - 44 questions
  • Sexuality and Gender - 19 questions
  • Social Sciences (Ethics/Legal/Professional) - 85 questions
  • Manage Care and Comply Regulations - 142 questions
  • Promote Safety and Minimize Infection - 145 questions
  • Health Promotion & Maintenance (Prevent Problems) - 381 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 47 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1167 questions
  • Reduction Risk (Post Procedure) - 99 questions
  • Physiological Adaptation (Care Ill Patients) - 4526 questions
  • Psychosocial (Mental Health Patient/Family) - 319 questions
  • Professional Practice - 131 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 5627 questions
  • Caring (Hope and Support) - 43 questions
  • Communication/Documentation (Oral, Written, EMR) - 54 questions
  • Teaching/Learning (Promotes Behavior Change) - 62 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 17 questions
  • Causes - 3507 questions
  • Classification - 535 questions
  • Differential - 3454 questions
  • Evaluation Diagnostic Tests - 1832 questions
  • Evaluation Lab - 2050 questions
  • Evaluation Monitoring - 547 questions
  • Evaluation Nuclear Medicine - 20 questions
  • Evaluation Procedures - 1154 questions
  • Evaluation Radiologic - 1770 questions
  • Health Maint Prevention Public Health - 263 questions
  • History Physical - 7170 questions
  • Legal - 48 questions
  • Patient Education - 417 questions
  • Prognosis Complications - 3592 questions
  • Toxicology - 358 questions
  • Treatment Medical - 3457 questions
  • Treatment Occupation/Physical Therapy - 67 questions
  • Treatment Prehospital/EMS/Disaster - 56 questions
  • Treatment Radiation - 26 questions
  • Treatment Rehabilitation - 37 questions
  • Treatment Surgical - 717 questions
  • Healthcare Ethics - 61 questions
  • Clinical Education - 95 questions
  • Environmental - 13 questions
  • Palliative - 25 questions
  • Treatment Manipulative - 8 questions
  • Airway Management - 32 questions
  • Pain Management - 70 questions
  • Sedation and Analgesic Management - 15 questions
  • Organ and Tissue Donation - 2 questions
  • Ventilatory Management - 18 questions
  • Research and Evidence-Based Medicine - 50 questions
  • Resource Utilization - 12 questions
  • Vulnerable Populations - 64 questions
  • Therapeutics (Drug treatment) - 1586 questions
  • Biostatics and Calculations - 11 questions
  • Drug Information - 1041 questions
  • Pharmaceutics (Safely dosing medications) - 447 questions
  • Pharmacokinetics (Drug movement in body) - 204 questions

SPEX Exam Articles (3,481)

We link each review question to its peer-reviewed, PubMed-indexed article from StatPearls authors and editors.
We make it easy for you to reinforce topic areas you excel at and fill knowledge gaps with source material.