Overview

4.7 out of 5 (64 Reviews)

Credits

1.00

Post-Assessment Questions

10

Start Date

1 Sep 2023

Last Review Date

6 Feb 2025

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


Unlimited Nurse CE

Stay up to date on the latest medical knowledge with 6743 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8017 hours of CE.

1 Year Unlimited Nurse CE

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Activity Description

Alprostadil is a synthetic prostaglandin E1 analog primarily used as a second-line treatment for erectile dysfunction in males when oral therapy has failed. This drug is also utilized in specific cases to temporarily maintain the patency of the ductus arteriosus in newborns with congenital heart defects until surgical intervention. For erectile dysfunction, alprostadil is administered via intracavernosal injection or intraurethral suppository, with combination therapies such as "Trimix" offering enhanced efficacy. In neonates, alprostadil’s vasodilatory properties help maintain ductal patency in conditions such as transposition of the great arteries or coarctation of the aorta. The use of this drug requires careful hemodynamic monitoring due to risks of instability. Common adverse effects include hypotension, flushing, and priapism, which require immediate intervention if prolonged. 

This activity reviews the indications, mechanism of action, administration, contraindications, and adverse event profile of alprostadil in the treatment of erectile dysfunction in males and the presurgical management of ductus arteriosus–dependent congenital heart defects in newborns. This activity also underscores the importance of interprofessional collaboration, including effective communication and coordination among healthcare team members, and the use of combination therapies to optimize patient outcomes and manage potential risks associated with alprostadil.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the appropriate indications for alprostadil use, including its role in erectile dysfunction and ductus arteriosus management in neonates.

  • Implement appropriate monitoring strategies for hemodynamic stability and adverse effects, such as hypotension and priapism, during alprostadil therapy.

  • Select appropriate adjunct therapies, such as combination drugs, to optimize outcomes in patients using alprostadil for erectile dysfunction.

  • Collaborate with an interprofessional healthcare team to ensure coordinated care and prompt intervention, optimizing patient outcomes in managing alprostadil's adverse effects.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

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Unlimited Nurse CE

Stay up to date on the latest medical knowledge with 6743 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8017 hours of CE.

1 Year Unlimited Nurse CE

Access to all the Unlimited Nurse CE activities in all specialties.

$39.99 per 1 year per user