Tricyclic Antidepressant Toxicity

Overview

4.7 out of 5 (18 Reviews)

Credits

1.50

Post Assessment Questions

11

Start Date

1 Jan 2023

Last Review Date

17 Jul 2023

Expiration Date

31 Dec 2025

Estimated Time To Finish

90 Minutes


 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Tricyclic antidepressants (TCAs) were introduced in the late 1950s for the treatment of depression. With the advent of selective serotonin reuptake inhibitors (SSRIs) and other new antidepressants, the use of TCAs has decreased, although they are still used to treat depression that has not responded to treatment with less toxic agents. In adults, TCAs are also used for migraine headache prophylaxis, treatment of neuralgic pain, including the pain associated with Ciguatera poisoning, and obsessive-compulsive disorder. In children, TCAs have been used to treat nocturnal enuresis. Despite the current limited use of TCAs, TCA-overdose-associated hospitalizations and fatalities are on the rise. This activity reviews the evaluation and management of tricyclic antidepressant toxicity and highlights the role of interprofessional team members in collaborating to provide well-coordinated care and enhance outcomes for affected patients.

UAN: JA4008195-9999-23-3191-H01-P

Target Audience

This activity has been designed to meet the educational needs of pharmacists.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the pathophysiology of tricyclic antidepressant toxicity.
  • Review the history and physical exam of a patient with tricyclic antidepressant toxicity.
  • Summarize the treatment options for tricyclic antidepressant toxicity.
  • Explain the importance of improving care coordination among interprofessional team members to improve outcomes for patients affected by tricyclic antidepressant toxicity.

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

Credit provided by Continuing Education, Inc, and StatPearls, LLC.

In support of improving patient care, this activity has been jointly planned and implemented by Continuing Education, Inc./University at Sea® and StatPearls, LLC. Continuing Education, Inc, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

This activity is designated for 1.50 contact hours for pharmacists.

FL Board of Pharmacy Tripartite, approval #20-608156.

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

Disclaimer

Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Continuing Education, Inc, reserve the right to cancel any course due to unforeseen circumstances. StatPearls and Continuing Education, Inc, will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls and Continuing Education are Equal Opportunity/Affirmative Action/Equal Access Institutions. 

 

 
 

Reviews

Thomas P. on 3/14/2021

brandi m. on 3/30/2021

Caleb P. on 7/28/2021

Jessica S. on 11/14/2021

MIA G. on 2/3/2022

Jacklyn V. on 5/26/2022

Finally some relatively straightforward questions that were pertinent.

Brian G. on 5/28/2022

Mary H. on 8/7/2022

Christine U. on 8/10/2022

Rayon S. on 11/15/2022

Nicole M. on 12/31/2022

Latoya R. on 1/25/2023

Ravi J. on 2/8/2023

Christine G. on 5/7/2023

Renford C. on 5/15/2023

Laxmi S. on 6/8/2023

Gregory P. on 6/16/2023

Sean K. on 7/17/2023

Unlimited Pharmacist CE

Stay up to date on the latest medical knowledge with 3469 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 4234.5 hours of CE.

6 Month Unlimited Pharmacist CE

Access to all the Unlimited Pharmacist CE activities in all specialties.

$59 per half year per user

1 Year Unlimited Pharmacist CE

Access to all the Unlimited Pharmacist CE activities in all specialties.

$79 per 1 year per user