BRCA1 and BRCA2 Mutations

Overview

4.6 out of 5 (26 Reviews)

Credits

1.00

Post Assessment Questions

7

Start Date

1 Mar 2023

Last Review Date

23 Jul 2023

Expiration Date

28 Feb 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Breast cancer genes BRCA1 and BRCA2 are tumor suppressor genes whose mutations significantly increase the likelihood of developing particular types of epithelial malignancies, namely breast and ovarian cancer. The management of patients with a BRCA1 and BRCA2 gene mutations is individualized and can include increased surveillance, chemoprevention using tamoxifen, a bilateral prophylactic oophorectomy, and/or bilateral prophylactic mastectomy. This activity describes the etiology, epidemiology, pathophysiology, screening, evaluation, and management of BRCA 1 and 2 mutations and shows the importance of the interprofessional team in educating patients about the risk of cancer and management strategy for such patients.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the pathophysiology of cancers associated with BRCA 1 and 2 mutations.
  • Outline the clinical presentation of patients with BRCA 1 and 2 mutations.
  • Explain the screening, monitoring, and treatment strategies in patients with BRCA 1 and 2 mutations.
  • Describe how an interprofessional team can collaborate to improve the diagnosis, monitoring, evaluation, and management of this condition and educate patients about the risk of cancer with BRCA 1 and 2 mutations.

Disclosures

StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

Disclaimer

Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 

 

 
 

Reviews

Deborah Z. on 7/16/2021

Michael B. on 9/19/2021

Christine Z. on 10/7/2021

Kimberly P. on 12/2/2021

Christopher N. on 3/19/2022

Alexei K. on 5/26/2022

Shannon j. on 6/29/2022

Vincent I. on 7/1/2022

Richard H. on 7/31/2022

thank you for the presentation. it was a good format. I learned more from the teaching points after the questions than the article.

Faith G. on 8/2/2022

Deborah Z. on 8/2/2022

Phu D. on 9/15/2022

Sara M. on 9/21/2022

Tamatha J. on 10/4/2022

Nancy O. on 11/17/2022

Charles W. on 11/20/2022

Larissa k. on 11/28/2022

Thank you for the overview

Brittany S. on 12/19/2022

Clark P. on 2/8/2023

Nikotah C. on 3/2/2023

Mary Y. on 3/10/2023

Malcolm B. on 4/12/2023

Aseeb R. on 4/17/2023

Kelsey H. on 6/30/2023

Amy H. on 7/5/2023

Rebecca L. on 7/10/2023

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